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🫁Синдром Гудпасчера – це прогресуюче аутоімунне захворювання легень і нирок, що проявляється поєднанням легеневих і ниркових геморагій.

🧬Причину синдрому остаточно не встановлено. Припускається генетична схильність до захворювання, маркером якої вважають HLA-DRw2.

🔹Основне у патогенезі захворювання – утворення аутоантитіл до базальних мембран капілярів ниркових клубочків і легеневих альвеол, які мають певну антигенну подібність. Ці антитіла відносять до класу IgG.

🔸Вони зв’язуються з антигенами базальних мембран у присутності С3-компонента компліменту, що призводить до імунного запалення нирок і альвеол легень.

Semper tiro
🫁Синдром Гудпасчера – це прогресуюче аутоімунне захворювання легень і нирок, що проявляється поєднанням легеневих і ниркових геморагій.

🧬Причину синдрому остаточно не встановлено. Припускається генетична схильність до захворювання, маркером якої вважають HLA-DRw2.

🔹Основне у патогенезі захворювання – утворення аутоантитіл до базальних мембран капілярів ниркових клубочків і легеневих альвеол, які мають певну антигенну подібність. Ці антитіла відносять до класу IgG.

🔸Вони зв’язуються з антигенами базальних мембран у присутності С3-компонента компліменту, що призводить до імунного запалення нирок і альвеол легень.
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Goodpasture syndrome - causes, symptoms, diagnosis, treatment, pathology
What is Goodpasture syndrome? Goodpasture syndrome is an autoimmune disease where the immune system attacks the basement membrane in the lungs and kidneys.

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Telegram auto-delete message, expiring invites, and more

elegram is updating its messaging app with options for auto-deleting messages, expiring invite links, and new unlimited groups, the company shared in a blog post. Much like Signal, Telegram received a burst of new users in the confusion over WhatsApp’s privacy policy and now the company is adopting features that were already part of its competitors’ apps, features which offer more security and privacy. Auto-deleting messages were already possible in Telegram’s encrypted Secret Chats, but this new update for iOS and Android adds the option to make messages disappear in any kind of chat. Auto-delete can be enabled inside of chats, and set to delete either 24 hours or seven days after messages are sent. Auto-delete won’t remove every message though; if a message was sent before the feature was turned on, it’ll stick around. Telegram’s competitors have had similar features: WhatsApp introduced a feature in 2020 and Signal has had disappearing messages since at least 2016.

🫁Синдром Гудпасчера – це прогресуюче аутоімунне захворювання легень і нирок

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