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How Non-steroidal anti-inflammatory drugs (NSAID) like aspirin cause peptic ulcer ?.
Core physiology book 📚 answer:
- These inhibit synthesis of prostaglandins from arachidonic acid.
- Since prostaglandins inhibit HCL synthesis and increase mucus
secretion, then chronic use of aspirin, which inhibits its formation from arachidonic acid, results in increased HCL secretion and decreasedmucus production causing peptic ulcer.

Physiology
How Non-steroidal anti-inflammatory drugs (NSAID) like aspirin cause peptic ulcer ?.
Core physiology book 📚 answer:
- These inhibit synthesis of prostaglandins from arachidonic acid.
- Since prostaglandins inhibit HCL synthesis and increase mucus
secretion, then chronic use of aspirin, which inhibits its formation from arachidonic acid, results in increased HCL secretion and decreasedmucus production causing peptic ulcer.
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How Non-steroidal anti-inflammatory drugs (NSAID) like aspirin cause peptic ulcer ?.

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