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Correct Answer - C
Ans. C: Anti-mitochondrial

Primary biliary cirrhosis is strongly associated with the presence of
anti-mitochondrial antibodies (AMA), which are diagnostic
PBC:
* Associated with CREST syndrome, sicca syndrome, auto-immune
thyroiditis, type I DM and IgA deficiency
* IgG AMA is detected in more than 90% of patients with PBC
* 90% of women are between 35 - 60 years
* Earliest symptom is pruritis
* Eventually hepatocellular failure and portal hypertension develops
* Lab findings:
- Increased serum alkaline phosphatase
- Increased serum 5-nucleotidase activity
- Increased gamma-glutamyl transpeptidase
- Serum bilirubin is usually normal
- Aminotransferase levels minimally increased
- Treatment: Ursodiol


@oncology_vid

Oncology
Oncology
Specific antibody associated with
primary biliary cirrhosis is: #PYQ#FMGE#NEETPG#INICET
Correct Answer - C
Ans. C: Anti-mitochondrial

Primary biliary cirrhosis is strongly associated with the presence of
anti-mitochondrial antibodies (AMA), which are diagnostic
PBC:
* Associated with CREST syndrome, sicca syndrome, auto-immune
thyroiditis, type I DM and IgA deficiency
* IgG AMA is detected in more than 90% of patients with PBC
* 90% of women are between 35 - 60 years
* Earliest symptom is pruritis
* Eventually hepatocellular failure and portal hypertension develops
* Lab findings:
- Increased serum alkaline phosphatase
- Increased serum 5-nucleotidase activity
- Increased gamma-glutamyl transpeptidase
- Serum bilirubin is usually normal
- Aminotransferase levels minimally increased
- Treatment: Ursodiol


@oncology_vid
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Correct Answer - C

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