گام به گام در تشخیص آزمایشگاهی کم‌خونی‌ها (3)- کم‌خونی‌های غیرمگالوبلاستیک @ماهنامه اخبار آزمایشگاهی

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Create: 2024-06-29 Update: 2025-06-29 01:47:38

گام به گام در تشخیص آزمایشگاهی کم‌خونی‌ها (3)- کم‌خونی‌های غیرمگالوبلاستیک
دکتر حبیب اله گل‌افشان

محمد اسماعیل خدمتی

دانشگاه علوم پزشکی شیراز
بخش سوم- کلیات
کم‌خونی‌های غیرمگالوبلاستیک:

کم‌خونی‌های غیرمگالوبلاستیک با MCV بالا دارای علل گوناگون هستند. در این حالت پیش‌سازهای گلبول‌های قرمز مرفولوژی خاص مگالوبلاستیک نداشته و گلبول‌های ماکروسیت مورفولوژی تخم‌مرغی (ماکرواوالوسیت) ندارند.

میزان MCV در اغلب موارد بین ۱۰۰ تا ۱۱۰ فمتولیتر و به ندرت بیشتر از ۱۲۰ فمتولیتر می‌شود. در خون‌سازی شتابزده (Accelerated Erythropoiesis) که متعاقب خونریزی، همولیز ناگهانی رخ می‌دهد، انبوه رتیکولوسیت‌های نارس به صورت گلبول‌های پلی‌کرومازی وارد خون می‌گردند و از آنجا که حجم رتیکولوسیت ۲۵ درصد بیشتر از حجم RBC است منجر به افزایــــش MCV می‌شـود. (Shift Reticulocytosis)
https://medlabnews.ir/%da%a9%d9%85%d8%ae%d9%88%d9%86%db%8c%d9%87%d8%a7%db%8c-%d8%ba%db%8c%d8%b1%d9%85%da%af%d8%a7%d9%84%d9%88%d8%a8%d9%84%d8%a7%d8%b3%d8%aa%db%8c%da%a9/

ماهنامه اخبار آزمایشگاهی

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ماهنامه اخبار آزمایشگاهی

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