homo_intelligence | United States America (US)

Create: 2025-06-30 Update: 2025-07-07 02:49:22

Вперше в історії вчені змогли «видалити» зайву хромосому при синдромі Дауна, але поки лише в лабораторії.

Японські дослідники використали технологію CRISPR‑Cas9, щоб знищити третю (зайву) хромосому у 21-шій парі, яка і викликає синдром Дауна.

Після видалення зайвої хромосоми клітини:
✅ почали ділитися активніше;
✅ показали нормалізацію експресії генів;
✅ поводилися майже як здорові.

Раніше вчені вміли лише «вимикати» хромосому, проте тепер її фізично прибрали. На жаль, це не ліки, не терапія, але це вже перша перемога на клітинному рівні.

Проблеми:
❌ наразі метод не готовий ані для тваринних моделей, ані для використання на людях через потенційні ризики та етичні питання;
❌ CRISPR може пошкодити інші хромосоми, до того ж безпечної «доставки» в організм наразі не існує.

P.S. На фото всесвітньо відома модель, яка має синдром Дауна. Еллі Голдстейн стала першою моделлю з особливими потребами, яка знялася для рекламної кампанії Gucci та журналу Vogue.

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Вперше в історії вчені змогли «видалити» зайву хромосому при синдромі Дауна

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