طـ℘ـب‌ و سـ℘ـلامتــے 🫀🩺️️️ | United States America (US)

Create: 2025-06-29 Update: 2025-06-29 20:33:16

ویتامین D🌞
ویتامین D یک پروهورمون محلول در چربی‌ست که نقش حیاتی در تنظیم متابولیسم کلسیم و فسفر و حفظ سلامت استخوان‌ها ایفا می‌کنه.
فرم فعالش یعنی 1,25-دی‌هیدروکسی‌کوله‌کلسیفرول (کلسیتریول) طی دو مرحله در کبد و کلیه ساخته می‌شه.
🔬 مراحل فعال‌سازی ویتامین D:
سنتز یا دریافت اولیه:

☀️ نور خورشید: پوست ما با تابش UVB، ۷-دهیدروکلسترول رو به کوله‌کلسیفرول (ویتامین D3) تبدیل می‌کنه.
🍳 رژیم غذایی: مثل ماهی‌های چرب، روغن کبد ماهی، زرده تخم‌مرغ، کره، جگر
D3 و D2
بعد از ورود به بدن، وارد کبد می‌شن.
مرحله اول – در کبد
:
🧬 کبد با کمک آنزیم ۲۵-هیدروکسیلاز، ویتامین D رو به ۲۵-هیدروکسی‌کوله‌کلسیفرول تبدیل می‌کنه.
📍 این فرم، اصلی‌ترین شاخص سنجش ویتامین D در آزمایش خون هست
!
مرحله دوم – در کل
یه:
کلیه با آنزیم 1-آلفا-هیدروکسیلاز، فرم بالا رو به
کلسیتریول (فرم فعال ویتامین D) تبدیل می‌کنه.
این آنزیم توسط هورمون پاراتیروئید (PTH) تحریک می‌شه.
❗️اگه PTH پایین باشه، مسیر فعال‌سازی منحرف شده و ویتامین D به فرم غیرفعال یعنی ۲۴,۲۵-دی‌هیدروکسی‌کوله‌کلسیفرول تبدیل می‌شود

طـ℘ـب‌ و سـ℘ـلامتــے 🫀🩺️️️

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246 viewsNasrin Rasa, Jun 29 at 04:11

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طـ℘ـب‌ و سـ℘ـلامتــے 🫀🩺️️️

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ویتامین D🌞

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