✨ *Mott Cell* ✨
🔶 Mature plasma cell that produces an excessive amount of immunoglobulins these Antibodies accumulate give Russell bodies (clustering of large white cytoplasmic inclusion)
🔶 Derived from rough endoplasmic reticulum
🔶 Found in both Benign and Malignant diseases ( e.g. Infections ,Multiple Myeloma)
🔶 The inclusions in Mott cells should not be confused with those in Burkitt Lymphoma.
● In Burkitt Lymphoma, the involved Lymphoblasts typically have delicate, immature nuclei, and the inclusions often appear as a "string of pearls" surrounding the nucleus.
● Mott cells are plasma cells containing Russell bodies, which are accumulations of immunoglobulin within the cytoplasm.
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