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Create: 2025-05-26 Update: 2025-07-10 08:43:47

بیماری ام‌اس
Multiple Sclerosis(MS)

🔵این بیماری، یک بیماری خود‌ایمنی مربوط به سیستم عصبی مرکزی است که با حمله سلول‌های ایمنی T‌کشنده به غلاف میلین محافظ در طول آکسون نورون‌ها ایجاد می‌شود.

⚫️آیا غلاف آسیب‌دیده ترمیم می‌شود؟

بله، غلاف میلین توسط الیگودندروسیت‌ها ترمیم می شود، اما چون سرعت این ترمیم از سرعت از بین رفتن آن توسط سلول‌هایT کشنده کمتر است، چندان به حساب نمی‌آید.

🔯انواع MS:
۱. عود‌کننده-فروکش‌کننده
RR MS
۲. پیشرونده ثانویه
SP MS
۳. پیشرونده اولیه
PP MS
۴. پیشرونده-عود‌کننده

🧠بررسی اسکن‌های MRI مغزی: وجود پلاک‌های بیشمار سفید رنگ در مغز
بررسی مایع مغزی-نخاعی: بالا بودن سطح آنتی‌بادی‌های خودی

⚠️علائم
مشکلات حرکتیDysarthria
مشکلات عصبیCharcots'
عدم‌کنترل حرکات چشم از‌جمله دوبینی در هر دو چشمNystagmus

💊درمان:
کورتیکو‌استروئیدها از‌جمله سیکلو‌فسفامید
پلاسمافرز: حذف آنتی‌بادی‌های خودی
ایمنو‌ساپرسنت‌ها مثل رکامبیننت بتا-INF

✍🏻حدیث محمدی

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بله، غلاف میلین توسط الیگودندروسیت‌ها ترمیم می شود، اما چون سرعت این ترمیم از سرعت از بین رفتن آن توسط سلول‌هایT کشنده کمتر است، چندان به حساب نمی‌آید.

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بیماری ام‌اس

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