🏅 Genetics A.S 🏅 | United States America (US)

Create: 2022-05-12 Update: 2025-07-06 07:26:16

🧬 مباحث مهم فصل ۱۵ 👈🏻

⚪️ از این فصل در دو سال آخر تست طرح شده و جزو فصل‌های داغ تو درس ژنتیک کنکور بهداشت هست؛ یک فایل ضمیمه هم پست بعد گذاشتم که نکاتش رو حتما بخونید :

🔴 مباحث مربوط به فعالیت N-استیل ترانسفرازی

🔴 واریانت‌های گلوکز ۶-فسفات دهیدروژناز

🔴 متابولیسم کومارین و وارفارین (توسط CYP2C9) (بسیار مهم)

🔴 متابولیسم دبریزوکوئین (توسط CYP2D6) (بسیار مهم)

🔴 هایپرترمی بدخیم (ژن RYR1) (مهم)

🔴 تیوپورین متیل ترانسفراز (ژن TPMT)

🔴 دی‌هیدروپیریمیدین دهیدروژناز (ژن DPYD و جهش IVS14+1G>A) (مهم)

🔴 دیابت MODY (بسیار مهم)

🔴 دیابت نوزادی (مهم)

🔴 جدول 1-15 (مهم)

🔴 دو مبحث در مورد آتالوران و ترکیب SMT022357

🔴 نکته بسیار مهم : دو بیمار پس از ژن درمانی بیماری SCID وابسته به ایکس (XL-SCID)، که در آن از رتروویروس برای انتقال ژن (IL2RG)γ-C استفاده شده بود، دچار لوسمی شدند؛ در ادامه مشخص شد که این ژن داخل پروتوآنکوژن LMO-2 بر روی کروموزوم 11 وارد شده و این پروتوآنکوژن را disrupt کرده است.خراب شدن این پروتوآنکوژن منجر به ایجاد لوسمی شد.

🔴 تمام مباحث مربوط به ویروس‌ها مهمن

📌 موفق باشید 🎆🎇

🧷 جهت دریافت جزوات دوره جمع‌بندی و آزمون‌های جامع پیام دهید : @Cyaxares

⛔️ کپی کردن پست‌های کانال، تنها با ذکر نام کانال بلامانع است!

#مباحث_مهم

کانال آموزشی آرش صفرزاده (@GeneticsAS)

🏅 Genetics A.S 🏅

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🧬 مباحث مهم فصل ۱۵ 👈🏻

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