#Ticket_to_Mains

तू न थकेगा कभी,
तू न रुकेगा कभी,
तू न मुड़ेगा कभी,
कर शपथ, कर शपथ, कर शपथ,
अग्निपथ अग्निपथ अग्निपथ।

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Pompe Disease

● Rare inherited disorder affecting one child per million

- Causes :

● Mutations in the GAA gene
● GAA gene produces enzyme acid alpha-glucosidase (acid maltase)
● Enzyme breaks down glycogen into glucose in lysosomes
● Mutations prevent effective breakdown of glycogen, leading to buildup in lysosomes

- Symptoms :

● Muscle weakness
● Respiratory issues
● Heart problems
● Difficulty swallowing

- Types :

● Infantile-onset: Symptoms start in first few months after birth
● Late-onset or delayed-onset: Symptoms appear later in childhood or adulthood

- Prevalence : Affects males and females equally

- Treatment : Enzyme replacement therapy (ERT)

Source : Indian Express

National Crime Records Bureau

● Repository of information on crime and criminals

- Establishment : 1986

- Affiliation : Comes under the Ministry of Home Affairs

- Origins : Set up based on recommendations of the Tandon Committee, National Police Commission (1977-1981), and Task Force of the Home Ministry
Functions

- Headquarters : New Delhi

- Key Initiatives :

● Crime and Criminal Tracking Network and System
● National Digital Police Portal
● National Database of Sexual Offenders
● Online Cyber-Crime Reporting Portal
● CyTrain
● Central Finger Print Bureau

- Publications : Compiles and publishes National Crime Statistics, including Crime in India, Accidental Deaths & Suicides, and Prison Statistics

Source : PIB

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🔥🔥Asset Reconstruction Companies (ARCs)🔥🔥

● In News:
- Reserve Bank of India (RBI) Releases Master Direction for Asset Reconstruction Companies (ARCs)

● About ARCs:
- ARCs are specialized financial institutions that purchase Non-Performing Assets (NPAs) from banks and financial institutions.

- NPAs are bad loans that are not generating income for the lenders.

- Role of ARCs:
1. Assist banks in cleaning up their balance sheets by acquiring their bad loans, allowing banks to focus on core banking activities.
2. Banks can sell their bad assets to ARCs at a mutually agreed value, relieving them from the burden of pursuing defaulters.

- ARCs are registered as companies under the Companies Act and with the RBI under section 3 of SARFAESI Act, 2002.

- Non-Banking Financial Companies under the RBI Act, 1934.

- 100% FDI is permitted.

- ARCs are prohibited from engaging in lending activities; they can only undertake securitization and reconstruction activities.

Business Standard

Green Turtle

- Scientific Name: Chelonia mydas

- Description:
● One of the largest sea turtles
● Sole herbivore among sea turtle species

- Coloration:
● Named for the greenish color of their cartilage and fat, not their shells
● In the Eastern Pacific, those with darker shells are called black turtles

- Diet: Grazes on seagrasses and algae

- Migration: Undertakes long-distance migrations between feeding grounds and hatching beaches

- Reproduction: Offspring sex determined by incubation temperature

- Distribution: Mainly found in tropical and subtropical waters

- Conservation Status:

● IUCN: Endangered
● CITES: Appendix I

Source : Forbes

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Lakadong Turmeric

● Considered one of the world's best varieties of turmeric

- Curcumin content: Approximately 6.8 to 7.5 per cent

● Darker in color, grown organically without fertilizers

- Found in : Lakadong area of Jaintia Hills, Meghalaya

Curcumin

● Polyphenol found in turmeric

● Targets multiple signaling molecules and demonstrates cellular activity

- Benefits include:

● Inflammatory conditions
● Metabolic syndrome
● Pain management
● Inflammatory and degenerative eye conditions
● Kidney health
● Effects primarily due to antioxidant and anti-inflammatory properties

- Other GI Products from Meghalaya :

● Garo Dakmanda (traditional dress)
● Larnai pottery
● Garo Chubitchi (alcoholic beverage)

Source : Times of India

Spices Board India

- Establishment : February 26, 1987, under the Spices Board Act 1986.

- Merger: Formed by merging the Cardamom Board and Spices Export Promotion Council.

- Nodal Ministry: Ministry of Commerce & Industry

- Functions: As a link between Indian exporters and international importers, involved in various activities across the spices sector.

● Oversees development of cardamom (small and large), focusing on production, productivity, and quality improvement.

● Implements post-harvest improvement programs for enhancing quality of 52 scheduled spices for export.

● Post-harvest quality improvement programs under 'Export Oriented Production.

● Promotes organic production, processing, and certification of spices.

●Develops spices in the North East region of India.

Source : Indian Express

Paradox of Thrift

● An economic paradox where an increase in autonomous saving leads to a decrease in aggregate demand, resulting in lower gross output and total saving.

- Narrow Perspective: Total saving may decrease due to individuals' attempts to increase their saving

- Broad Perspective: Increase in saving may be harmful to an economy overall, despite being beneficial for individuals

- Fallacy of Composition suggesting that what is true for parts may not hold true for the whole

- Stated : As early as 1714 in "The Fable of the Bees"

- Popularized by : John Maynard Keynes

● Impact : More saving leads to less spending, which can worsen a recession

Source : The Hindu
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